MALIGNANT HYPERTENSION (Robbins pp 983, Fig 21-50)

on 26.11.07 with 0 comments



This occurs after long standing injury to the arterioles. This results in fibrinoid necrosis of arterioles, hyperplasia of intima narrowing of lumen≫ malignant hypertension. The afferent arterioles have depleted blood flow ≫ rennin-angiotensin system activated ≫ more hypertension ≫ cycle continues.

Morphology: fibrinoid necrosis of arterioles + onion-skin lesion.

Category: Pathology Notes

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