Chondrosarcoma

-Is a malignant tumor of chondrogenic origin that remains essentially cartilaginous throughout its evolution.

1. How common is Chondrosarcoma? What age group?

   1. Represents the third most common primary malignant bone tumor, following multiple myeloma and osteosarcoma.

   2. Age group is 40-60 years 2:1 male predominance.

2. Key clinical features

   1. Pain usually presents late in the disease process, often after large soft tissue masses develop

   2. Severe pain follows pathologic fracture

   3. The most common sites are the pelvis, proximal femur and humerus, ribs, scapula, sternum, craniofacial bones, distal femur, and proximal tibia. The normal variance notes states that Chonndrosarcoma is the m/c primary malignant tumor of the hand.

3. Key radiological features

   1. Round or oval radiolucencies with ill-defined margins evident.

   2. Lesions re metaphseal or diaphyseal

   3. Endosteal scalloping occurs secondary to pressure erosion from the enlarging lobular mass

   4. Popcorn matrix calcification in the lesion occurs in 2/3 of cases; 1/3 are purely radiolucent

   5. Laminated or speculated periosteal response occurs

   6. Metastatic disease is usually to lung

4. Prognosis

   1. Prognosis is good, with 90% survival after early surgery

Category: Orthopedics Notes , Tumors Revision