World Health Organization (WHO) clinical definition of AIDS in Africa
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19.10.09
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You are here: Home » Medical Subject Notes , Medicine Notes » World Health Organization (WHO) clinical definition of AIDS in Africa
AIDS in an adult is defined as the presence of at least 2 major criteria and at least 1 minor criterion (in the absence of any other cause of immunosuppression such as cancer, cytostatic therapy, prolonged steroid therapy or malnutrition). These criteria of course do not have 100% sensitivity and they are not 100% specific. They are only intended as guidelines. This definition should not be used by clinicians to declare the diagnosis without the result of a HIV-test. New definitions have been proposed since HIV-tests have become more available.
| Major | Weight loss > 10 % of earlier weight |
| Chronic diarrhoea > 1 month | |
| Prolonged high temperature > 1 month (constant or intermittent) | |
| Minor | Generalised pruritic papulous cutaneous rash |
| Generalised lymph node swelling | |
| Persistent cough > 1 month (when no TB) | |
| Chronic Candida infection in mouth/throat | |
| Recurrent Herpes zoster | |
| Chronic progressive and generalised Herpes simplex infection, resulting in painful genital ulcerations, not responding to antibiotics | |
| Other | The presence of disseminated Kaposi's sarcoma or cryptococcal meningitis is in itself sufficient for AIDS diagnosis. |
Category: Medical Subject Notes , Medicine Notes
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