Global cerebral ischemia (from hypoperfusion of the entire brain)
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You are here: Home » Pathology Notes » Global cerebral ischemia (from hypoperfusion of the entire brain)
Selective vulnerability
Some neurons are more susceptible to ischemia (Purkinje cells are very vulnerable)
Not due to reduction of blood flow
Can see a ribbon-like area of necrosis since certain areas of the cerebral cortex are more vulnerable (called laminar infarcts)
Watershed infarcts
Infarcts at borders between arterial supply regions
These low perfusion areas are at higher risk of injury even with mild hypoxia
Respirator brain – autolytic softening of brain in veggies on respirators
Category: Pathology Notes
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