Staphylococcal scalded-skin syndrome

on 19.9.08 with 0 comments



  • in the adult, might see bullus impetigo, which is impetigo + a couple of filled bullae on skin surface

  • 5% of S. aureus produce the hemolytic toxins ETA and ETB

  • these hemolysins target desmoglian in superficial epidermis and lead to their dissolution

  • there is sloughing of the skin and vesicles at the level of the stratum granulosum PDF 14


Pathogenesis of staphylococcal scalded-skin syndrome

  • if you inject an animal with anti-desmoglian antibodies, epidermis separates from dermis

  • if you inject the toxin, epidermis separates from the underlying dermis as well




Category: Microbiology Notes

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