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| Adrenergic | Effects |
| Cholinergic |
Iris: Radial Muscle | N.E., alpha-1 receptor | contraction (mydriasis) | ----- | ||||||
Iris: Sphincter muscle | ----- | ----- | contraction (miosis) | ||||||
Ciliary Muscle | N.E., beta2 receptor | relaxation (far vision) | contraction (near vision) | ||||||
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| Adrenergic | Effects |
| Cholinergic |
|
Sino-atrial (SA) Node | beta1; beta2 | increase rate | decrease rate (vagal) |
Atrial muscle | beta1, beta2 | increased: contractility, conduction velocity | decreased: contractility, action potential duration |
Atrio-ventricular (AV) node | beta1, beta2 | increased: automaticity*, conduction velocity | decreased conduction velocity; AV block |
His-Purkinje System | beta1, beta2 | increased: automaticity, conduction velocity | ------ |
Ventricles | beta1, beta2 | increased: contractility, conduction velocity, automaticity, ectopic pacemaker | small decrease in contractility |
Skeletal Muscle
Adrenergic Effects |
| | Cholinergic |
Skeletal Muscle | beta2 | increased: contractility; | ---------- | ||||
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Adrenergic Effects |
| | Cholinergic |
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Liver | alpha1;beta 2 | glycogenolysis and gluconeogenesis | -------- |
Category: Pharmacology Notes
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