Side Effects

Drug

Chemical Class

CPZ Equiv

DA₂ Affinity

Ch-M Affinity

Adr₁ Affinity

Extra-pyramidal

Anticholinergic Sedation Hypotension

Low potency

Chlorpromazine

Largactil

Aliphatic phenothiazine

100

+

+++

+++

Thioridazine

Mellaril

Piperidine phenothiazine

100

+

+++

+++

Midpotency

Perphenazine

Trilafon

Piperazine

Phenothiazine

8

++

++

++

Loxapine

Loxapac

Dibenzoxazepine

10

++

++

++

High potency

Haloperidol

Haldol

Butyrophenone

2

+++

-

+

Fluphenazine

Moditen

Piperazine phenothiazine

2

+++

-

+

Atypical

Clozapine

Clozaril

Dibenzodiazepine

80

+

+++

++

Absent

High

Risperidone

2

++

-

++

Low

Low