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Nocturnal gastric acid reflux results in significant acidic gastric fluid entering the oral cavity. Patients complain of a bitter, acid taste in their mouth. Chronically, this acidic environment results in significant enamel erosion and rampant caries.
Pharmacological Mgt of GERD: - acid suppression (best: proton pump inhibitors)
- alter gastric-esophageal dynamics (e.g., metoclopramide [Reglan])
- increase esophageal peristalsis
- increase esophageal sphincter tone
- promote gastric emptying
- antacids mask the symptoms of dyspepsia
Category:
Pharmacology Notes
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