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Indications for Lansprazole and Omeprazole (PPIs)Heartburn and GERD symptoms; erosive esophagitis, maintenance of healed erosive esophagitis, H. pylori eradication to reduce the risk of duodenal ulcer recurrence (combo tx includes Prevacid [PPI], Amoxicillin [penicillin derivative], and Biaxin [a macrolide antibiotic]); active and maintenance of healed duodenal ulcers; active benign gastric ulcers; hypersecretory conditions including Zollinger-Ellison Syndrome.
H. pylori Treatment (FDA approved, 1996)First 2 weeks: Omeprazole (40 mg/day) & Clarithromycin (500 mg/day)
Days 15-28: Omeprazole (20 mg/day)
74-83% eradication achieved!
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Pharmacology Notes
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