HIV: Non-nucleoside analogues of reverse transcriptase inhibitors

on 30.9.09 with 0 comments



Product

Daily dose

Side-effects

Precautions

Efavirenz (Stocrin®)

200 mg

1 x 600 mg

Crystalluria, influenza, depression

Concentration disorders

Teratogenic,

Not active against HIV-2

Not with saquinavir

Delavirdine (Rescriptor®)

100 mg tablet

3 x 400 mg

Rash, Stevens-Johnson, headache

Not with antacids.

Not active against HIV-2.

Nevirapine (Viramune®)

200 mg

2 x 200 mg maintenance dose

Cutaneous rash

Gradually increase dose.

Begin 200 mg per day x 2 weeks

Then 400 mg per day

Not with saquinavir

Category: Medical Subject Notes , Pharmacology Notes

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