CAN WE USE AN NSAID IN CONJUCTION WITH WARFARIN?
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You are here: Home » Medical Subject Notes , Pharmacology Notes » CAN WE USE AN NSAID IN CONJUCTION WITH WARFARIN?
Risk of a bleeding ulcer:
- Untreated pts: 2.1/1000 pt years
- Anticoagulant use: 8.9/1000 pt years
- NSAID alone: 8.3/1000 pt years
- NSAID + anticoagulant: 26.3/ 1000 pt years (*** 13 TIMES THE RISK of GI bleeding compared to non drug users!!!)
Conclusion: “We would recommend that no NSAID be used in anticoagulated pts”
If a pt is taking Warfarin, low-dose (81mg) Aspirin may be safely used. For analgesics, use acetaminophen, tramadol or hydrocodones, etc instead of NSAIDs.
Category: Medical Subject Notes , Pharmacology Notes
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