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| Nephrotic syndrome | Nephritic syndrome |
Proteinuria | >3-3.5g/dy (massive) | <3.0g/dy |
Onset | insidious | abrupt |
Renal Fn | Initially normal | Present w/ BUN & creatinine |
hematuria | sometimes seen | often |
Nephrotic syndrome Massive proteinuria caused by permeability & accomp’d by hypoalbuminemia, edema, hyperlipidemia, & lipiduria
Etiology of nephrotic syndrome
33% of adults & 10% of kids caused by systemic dz’s (DM [most common cause], SLE, & amyloidosis)
66% of adults & 90% of kids is 2 to 1 glomerular disease such as MCD, MN, or MPGN
Other assoc’d dz’s
Hodgkin’s disease assoc’d w/ MCD
Breast, Lung & GI cancers assoc’d w/ MN [most common tubular dz assoc’d w/ malignancy]
NOTE: if pt >45 yo & NS think malignancy
5% of PSGN can have NS
IgA nephropathy can have
Category: Nephrology Notes
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