Diagnosis: filamentous fungi
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9.10.08
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infiltrate with cavity on CXR or chest CT suggestive
difficult to grow mold from sputum or bronchoscopy wash
direct exam for hyphae has low sensitivity
serum antigen assay: galactomannan is useful to identify aspergillus
PCR-based assays have had variable results; further, none are commercially available
Radiology
10% on CXR
consolidation is common
nodular shadows with cavitation
thin or thick wall cavities
pleural effusion
CT scan plays a major role in early dx
most distinctive early lesions are one or more small nodules surrounded by a halo
Category: Microbiology Notes
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