Infection and specific immunity

on 23.5.08 with 0 comments



If the infection reaches a threshold level (i.e.: virulence is high, and dose is high) and eludes the innate arm of the immune response, then adaptive immunity is activated. This occurs as a result of antigen presentation to naïve T cells at the lymph nodes, which get activated and then travel to the site of infection to elicit a response (cell mediated), or antigen may remain in the lymph nodes, activating B cells for antibody production (humoral). What determines whether a T or B cell response is initiated? That depends on the type of cytokines produced by the innate immune response.

Category: Pathology Notes

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