Restrictive lung disease functional features
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extensive interstitial fibrosis
restricted expansion of lung
airway flow is not impaired
distortion of normal structural arrangement of blood-gas exchange
Etiology
unknown
idiopathic pulmonary fibrosis: 65%
post-ARDS
environmental
inorganic
organic
drug- or treatment-related
chemo
ionizing radiation/oxygen
immunologic
hypersensitivity pneumonia
sarcoidosis/Wegener’s granulomatosis
Sarcoidosis
a non-caseating granuloma. that is the only histological difference between it and TB
Interstitial lung disease/fibrosis is the end stage of a wide variety of pulmonary injuries. functionally, it is restrictive lung disease
Category: Pathology Notes
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