Importance of microbial surface molecules
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You are here: Home » Microbiology Notes » Importance of microbial surface molecules
the surface is important for attachment of the pathogen to the host
surface is a target of innate and adaptive immunity
consequently, many surface molecules are virulence factors—e.g. polysaccharide capsules of Streptococcus pneumoniae, Influenza
Microbial surface molecules
major targets of protective antibodies
targets of vaccines (e.g. Hemophilus influenzae type B)
specific antibodies against the surfaces of different isolates is the basis of serotype
Streptococcus pneumoniae: over 80 serotypes; 23 most common are included in the vaccine
Neisseria meningiditis: 13 serotypes; 4 are included in the vaccine
Category: Microbiology Notes
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