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a bone tumor seen in Paget’s disease
Photomicrograph of Paget’s sarcoma
zigzag cement lines, extremely irregular
if you view this under polarized light, you get a lot of nonpolarizing material, which reflects Paget’s disease
Bone is susceptible to fracture in Paget’s sarcoma
neoplastic change is very hard to clear
neurologic—sensory and motor problems—stem from vertebral involvement
in some stages, there is high-output cardiac failure, although this is very unusual
Main things to remember
it’s nothing much of the time
picture-frame vertebra
if it’s more progressive, deafness, blindness, thickness of skull, secondary osteoarthritis
Category: Pathology Notes
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