Ewing’s sarcoma

-Is a primitive primary malignant tumor of bone it is composed of tumor cells derived from the connective tissue framework of bone marrow

1. How common? Age group?

   1. 7% of all primary bone tumors. 4^th m/c primary malignant bone tumor behind (multiple myeloma, osteosarcoma, and chondrosarcoma).

   2. 10-25 years of age

2. Key clinical features

   1. Mimics: Infection; systemic signs of slight fever, secondary anemia leukocytosis, and increase ESR

   2. Affects long tubular bones of the Lower extremity.

3. Key radiologic features

   1. Saucerization: Cortical saucerization is a characteristic sign. This irregular defect effaces the outside of the bone occasionally, exhibiting a marginal scalloping effect.
      

   2. Classic presentation is a diaphyseal permeative lesion with a delicate onion skin or peel periosteal response.

   3. The most common primary malignant bone tumor to metastasize to bone

Category: Orthopedics Notes , Tumors Revision