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Factor | Blastic Metastases | Paget’s Disease | Hodgkin’s Disease |
Age (years) | >45 | >50 | 20-40 |
Increased density | +++ | +++ | +++ |
Expansion | ---- | +++ | |
Anterior Scalloping | ---- | ---- | +++ |
Acid phosphatase | +++ | ---- | ---- |
Alkaline phosphataes | ++ | +++ | ++ |
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Pelvis includes protrusio acetabuli with Kohler’s teardrop and thickening of pelvic brim
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Long bones: the tibia is the m/c lytic site
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Complications
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Deformity of bone include: Shepherd’ crook deformity of the proximal femur (coxa vara), Saber shin (ant. Tibial bowing), Protrusio acetabuli.
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Cranial nerve neuropathies b/c foramen get smaller.
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Linked to increased wear and tear, early DJD
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Increased alkaline phospatase (up to 20x normal)
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Category: Orthopedics Notes
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