Blood Pharmacology MCQ 1 With Answer

The Correct option is D

Discussion

• Option A & B are factually incorrect.
• Option C is incorrect. Desmopressin is a synthetic analogue of 8-arginine vasopressin (ADH). The drug is less vasoactive than the original hormone but still has a strong antidiuretic effect.
• Option D is correct. Desmopressin initiates the release of factor VIII and von Willebrand factor. When administered vasopressin shortens the bleeding time in patients with congenital or acquired defects in the primary hemostasis. The drug maybe used as prophylaxis or treatment of bleeding complications due to congenital disorders such as von Willebrand’s disease, thrombopathies and mild hemophilia A, or in acquired defects in primary hemostasis like uremic thrombopathy, liver cirrhosis and aspirin induced thrombopathy.
• Option E is incorrect. Since Desmopressin does not increase the activity of Factor VIII, it only increases its synthesis and release.