Pressures that help or decrease GFR

• Pressure (blood pressure)

  • Hydrostatic pressure

  • Osmotic pressure

  • High enough to leak, but low enough to let is go

  • Pressure must be low enough to receive the pressure from the bowman's capsule

• Dehydration

  • Higher osmotic pressure - resist fluid out flow

• Hypertensive

  • Increased GFR

    • Higher pressure

    • Proteins then can leak out

• Stone @ base of bladder

  • Cause a back up al the way to the bowman's capsule

  • Decrease GFR

  • Increased serum levels of urea

    • Obstruct the system (reduce GFR) - cannot get rid of it

      • Alternate input sites are full already

    • Dehydration

Category: Physiology Notes , Surgery Notes