Indications and dose ranges (adults) for some commonly used prescription NSAIDs

Etodolac (Lodine) is widely promoted in dental conferences, because the manufacturers are looking for a dental use. It’s approved for dental analgesia, but not as popular as ibuprofen. There are differences in indications between all these drugs . Ketorolac is the only injectable NSAID available right now, approved only for acute pain. After intra-muscular injection, there is a prescription for 3 days oral Ketorolac. Ibuprofen can be used for fever, pain, arthritis, dysmenorrhea. Same with aspirin. Same indications with naproxen, plus gout and ankylosing spondylitis

Does pretreatment with an NSAID before a dental procedure reduce the extent and severity of post-surgical or post-extraction pain and inflammation? Is the time course of the pain and inflammation less if an NSAID is given one hour pre-surgery?

To answer,we see that both pre- and post-operative ibuprofen dosages are essentially the same in analgesia effectiveness. Some oral surgeons argue that pre-dose ibuprofen modifies the time course of post-extraction inflammation and swelling. As far as analgesia though, it doesn’t mean that they will come out of surgery with no pain.

Category: Pharmacology Notes