ISOFLURANE
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25.4.08
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-improved version of enflurane
-safer than halothane or enflurane
-hypotension similar to halothane
-less potent than halothane but more than enflurane (MAC = 1.2%)
-elevated HR (tachycardia) and decreased TPR maintain cardiac output
-no arrhythmias or seizures
-little metabolized (0.5%), which is excellent! There’s little danger of toxicity
-pungent, can cause laryngospasm and coughing
-danger of malignant hyperthermia (MH)
Category: Pharmacology Notes
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