Acid Base Pharmacology MCQ 1 With Answer

on 22.3.08 with 0 comments



An intravenous infusion of 8.4% sodium bicarbonate to a healthy adult may cause:
  1. Hypotonicity hypertonic – causing incr BV +/- CCF
  2. Intracellular acidosis
  3. Ionised hypercalcaemia
  4. Respiratory alkalosis
  5. Rebound metabolic acidosis


Click Here For Answer & Discussion

The Correct option is B

Discussion

  • Option A is incorrect. It will lead to hypertonicity, increased blood volume , which may or may not cause Congestive cardiac failure.
  • Option B is correct. Intracellular acidosis occurs as a result of CO2 moving intracellularly, especially if not compensatorily hyperventilated to offset increased CO2 production.
  • Option C is incorrect. Think carpopedal spasm (Ganong 369 and 57) – increased pH so increased plasma protein ionisation so increased Ca2+ binding so decreased free Ca2+.
  • Option D & E are incorrect. There might be respiratory acidosis and rebound metabolic alkalosis.


Category: Pharmacology Notes

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