Psoriasis

on 27.2.08 with 0 comments



Description and Symptoms

Scaly, red plaques that tend to affect the knees, elbows, scalp and sacrum. Most patients have a few small asymptomatic plaques, however some have widespread lesions & /or pruritus. 1% incidence. Possible autosomal dominant inheritance with variable penetrance.

Diagnosis

Clinical appearance, though may confirm with a biopsy.

Pathology

An inflammatory reaction in the skin altered by environmental and genetic factors.

Principles of Therapy

Aggressiveness of therapy must be tailored to clinical situation. Many options available: topical (steroids, calcipotriene, retinoids), ultraviolet light (A&B), and systemic (methotrexate, retinoids, cyclosporine, TNF-alpha inhibitors).


Category: Dermatology Notes

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