Glaucoma

on 24.1.08 with 0 comments



Pharmacology of the Eye

“The eye is a good example of an organ with multiple ANS functions, controlled by several different autonomic receptors.” (Katzung)

Increased intraocular pressure: Untreated -> blindness

Glaucoma:

  • Open-angle (wide, chronic) – treated with betablockers and other agents
  • Closed-angle (narrow-angle) – dilated iris can occlude outflow. Pilocarpine or surgical removal of part of iris (iridectomy)
Glaucoma treatment

  1. a-Agonist: Increase ­Outflow
  2. M-Agonists: ­Increase Outflow
  3. b -Blocker: decrease Secretion
  4. a2-Agonist: decrease Secretion
  5. Prostaglandins: ­Increase Outflow
  6. Carbonic acid inhibitors: Decrease Secretion

Category: Ophthalmology Notes

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