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- Definition- Essential organic substances needed in small amounts in the diet for normal function, growth and maintenance of the body 
- Yield no energy to the body, they often participate in energy-yielding reactions 
- A, D, E, K are fat soluble 
- B, C are water soluble 
- B, K function as parts of coenzymes (compounds that help enzymes function) 
- Can’t be synthesized in the human body 
- To be classified as a vitamin, a compound must meet criteria - Body is unable to synthesize enough of the compound to maintain health 
- Absence of the compound from the diet for a defined period of time produces deficiency symptoms 
 
- Few vitamins have also proved useful in treating several nondeficiency diseases 
- These medical applications require administration of mega doses (well above typical human needs for the vitamins 
- Mega doses of a form of niacin can be used as part of blood cholesterol-lowering treatment for certain individuals 
- Other examples of medical use include forms of vitamin D in the treatment of psoriasis 
STORAGE OF VITAMINS IN THE BODY
- Fat-soluble vitamins are not readily excreted from the body 
- Excess amounts of the water-soluble vitamins are generally lost from the body quite rapidly, partly because the water in cells dissolves these vitamins and excretes them out of the body via the kidneys 
- Water-soluble vitamin B-6 and vitamin B-12 are exceptions 
- An occasional lapse in the intake of even water-soluble vitamins generally causes no harm 
- Symptoms of a vitamin deficiency occur only when that vitamin is lacking in the diet and body stores are essentially exhausted 
- Average person must consume no thiamin for 10 days or no vitamin C for 20-40 days before developing the first symptoms of deficiency of these vitamins 
VITAMIN TOXICITY
- Fat-soluble vitamins can easily accumulate in the body and cause toxic effects 
- Toxicities of the fat-soluble vitamin A is the most frequently observed 
- ‘one-a-day’ type of multivitamin and mineral supplement usually contains less than 2 times the Daily Values of the components regular use of these products is unlikely to cause toxic effects in men 
- but highly potent sources of vitamin A can cause problems 
PRESERVATION OF VITAMINS IN FOODS
- substantial amounts of vitamins can be lost from the time a fruit or vegetable is picked until it is eaten 
- water-soluble vitamins can be destroyed with improper storage and excessive cooking 
- heat, light, exposure to the air, cooking in water, and alkalinity are all factors that can destroy vitamins 
- the sooner a food is eaten after harvest, the less chance of nutrient loss 
- if the food is not eaten within a few days, freezing is the best preservation method to retain nutrients 
- frozen vegetables and fruits are often as nutrient-rich as freshly picked ones 
- fruits and vegetables are often frozen immediately after harvesting 
Category: Biochemistry Notes
 



 
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