MALIGNANT MIXED MULLERIAN TUMOUR – MMMT (Robbins pp 1063)

In MMMT (these are highly malignant) – there is a bit of both types of tumours: epithelial, and mesenchymal. There is malignant glandular pattern and malignant stromal elements. The stromal elements may be: cartilage, muscle, osteoid etc. Both types of tissue derive from one cell (monoclonal) – because epithelial markers are present in stromal cells. These tumours occur in post-menopausal women.

PROLIFERATING / BORDERLINE TUMOURS

In these types of tumours, there is evidence of proliferation and spread but all of this is benign. Serous tumours are most common. In serous tumours, the epithelium proliferates uncontrollably, but don’t invade stroma. They are cystic tumours with luminal/surface papillae. These tumours are not cancer! (i.e.: malignant). The mucinous variety is similar in that epithelium is uncontrollably proliferating, except now there is mucin. Arrangement is multicystic.

IMPLANTS

These are just spreads of primary cancers.

PSEUDOMYXOMA PERITONEI

Refer above. Refer to pp 1071.

Category: Pathology Notes