INFLAMMATORY LESIONS OF THE BREAST

on 20.11.07 with 0 comments



Acute Mastitits: This occurs during nursing as cracks begin to appear in the nipples. This allows Staph + Strep to invade --> acute inflammation --> breast abscess.

Fat Necrosis: Occurs 2nd to trauma
Macroscopy: irregular hard mass of orange/brown colour (haemoglobin derived pigments). Microscopy: central necrotic fat surrounded by lipid laden macrophages and neutrophilic infiltration. Later on: fibrovascular changes wall it off. Later on: fibrosis associated with foamy macrophages laden with haemosiderin.

Breast abscess: Results from acute mastitis or rupture of a duct.
Microscopy: central cavity filled with neutrophilic debris surrounded by inflamed tissue --> eventually fibrosis occurs.

Category: Pathology Notes

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