Cluster designations

Found on:

cluster designation:

binds to:

effects.

CD 2

LFA-3

T helper

CD 4

MHC II

Exogenous Ag

T killer

CD 8

MHC I

Endogenous Ag

leukocyte

CD11 / CD18

ELAM-1

adherence to endothelium

CD 28

B7 (CD 80 / CD 86)

co-stimulation. ÝIL-2.

endothelium

CD 34

L-selectin

binds lymphocytes

B

CD 40

CD 40 ligand on T

class switching.

cancer

CD 44

endothelium

needed for metasis

endothelium

CD 54

ICAM

CD 18 LFA1(integrin)

binds lymphocyte

endothelium

CD 106 VCAM

CD29/CD49 VLA

binds monocyte

endothelium

ICAM (Ig like)

LFA-1 (integrin)(CR3)

Mo-1

lymphocyte

neutrophil

endothelium

VCAM (Ig like)

VLA-1 (integrin)

monocyte

endothelium

E-selectin (lectin)

CD 15 glycolipids

neutrophil, T, monocyte

endothelium

P-selectin (lectin)

glycolipids

neutrophil, monocyte

non-CA cells

MHC

NK cells

phosphatase turns off nk