What cancers are associated with smoking? Why does smoking cause cancer?

• LUNG CANCER

  1. Smoking causes progressive alterations in the lining epithelium of the respiratory tract. Changes begin with a rather innocuous basal cell hyperplasia and squamous metaplasia and progress to squamous dysplasia and carcinoma in situ, before culminating in invasive cancer.

  2. 90% of lung cancers occur in active smokers or those who stopped recently

• RENAL CELL CARCINOMA

• BLADDER TUMORS

• ORAL CANCER

• CARCINOMA OF THE LARYNX

• ESOPHAGEAL CARCINOMA

• CARCINOMA OF THE PANCREAS

• VULVAR CARCINOMA

Category: Pathology Notes