Properties or RNA viruses
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--Most RNA viruses replicate in the cytoplasm. Influenza viruses and retroviruses replicate in the nucleus.
--Cells cannot replicate RNA, all RNA viruses must encode a RNA-dependent RNA polymerase. Retroviruses encode a reverse transcriptase.
--The genome structure determines the mechanism of transcription and replication.
--RNA viruses are prone to mutations because they lack proof-reading machinery.
--The genome structure and polarity determines how viral mRNA is synthesized and how proteins are processed.Category: Microbiology Notes
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