Cutaneous T-Cell Lymphoma (CTCL, Mycosis Fungoides)
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You are here: Home » Dermatology Notes » Cutaneous T-Cell Lymphoma (CTCL, Mycosis Fungoides)
Malignant patches progressing to plaques, tumors and ulcers on the skin. Usually very slow course and delayed diagnosis (6-8 years after onset). Sezary syndrome is more aggressive and manifested by diffuse erythema.
Diagnosis
High index of clinical suspicion. Many biopsies often needed. 5-7 year delay from onset to diagnosis is typical.
Pathology
Epidermal attack by malignant T Cell clones.
Principles of Therapy
Skin involvement often treated with PUVA, Nitrogen Mustard &/or Retinoids.
Tags: Mycosis Fungoides, Lymphoma, dermatology
Category: Dermatology Notes
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