CNS Stimulants

on 9.7.05 with 0 comments



  1. Amphetamine

    1. Animal Models: stereotyped behavior

    2. Mechanism of Action

      1. synthesis and release of catecholamines


        1. tyrosine hydroxylase: inhibited by alpha methylparatyrosine (-MPT)

        2. reserpine: inhibits vesicular storage


  1. Therapeutic Indications

    1. Anorectic Agents

      1. amphetamine

      2. fenfluramine

      3. mechanism of action

      4. advantages & disadvantages

      5. mazindol

      6. phenylpropanolamine

    2. Attention Deficit Disorder

      1. amphetamine

      2. a paradox

      3. advantages & disadvantages

      4. methylphenidate

      5. mechanism of action

      6. pemoline

      7. advantages & disadvantages

    3. Narcolepsy

    4. Sports

Category: Pharmacology Notes

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