Left Ventricular Hypertrophy

Hypertension: There are three
major things central to hypertension. They include increased systemic vascular
resistance, increased vascular stiffness and increased vascular responsiveness
to stimuli.
Hypertrophy: Cells increase in size to deal with increased workload. With increased vascular resistance and vascular stiffness in the circulation distal to the heart (aka increased cardiac afterload), the heart cells in the left ventricle get bigger, leading to LVH.
LVH is a relatively early response to hypertension; it is even demonstrated on echocardiogram of children and adolescents with borderline hypertension. LVH may even begin before hypertension because the same factors (angiotensin II, norepinephrine, epinephrine, increased sympathetic drive, and endothelin) promoting both HTN and LVH .
Hypertrophy: Cells increase in size to deal with increased workload. With increased vascular resistance and vascular stiffness in the circulation distal to the heart (aka increased cardiac afterload), the heart cells in the left ventricle get bigger, leading to LVH.
LVH is a relatively early response to hypertension; it is even demonstrated on echocardiogram of children and adolescents with borderline hypertension. LVH may even begin before hypertension because the same factors (angiotensin II, norepinephrine, epinephrine, increased sympathetic drive, and endothelin) promoting both HTN and LVH .