Cardiac Glycosides:

1. Pathophysiology of Congestive Heart Failure

2. Therapeutic Classes

1. Cardiac glycosides

   1. Agents

      1. digitoxin

      2. digoxin

   2. Pharmacodynamics

   3. Pharmacokinetics

   4. Uses

      1. congestive heart failure: all degrees

      2. atrial fibrillation

      3. atrial flutter

      4. paroxysmal atrial tachycardia

      5. cardiogenic shock

   5. Adverse effects

      1. gastrointestinal

      2. central nervous system

      3. cardiac

      4. other

      5. treatment

2. Amrinone lactate

   1. Pharmacokinetics

   2. Use

   3. Adverse effects

3. Group III

   1. bretylium

   2. amiodarone

   3. Pharmacodynamics: increases prolongation of phase 3

4. Group IV: verapamil

   1. Pharmacodynamics

      1. depresses automaticity

      2. depresses A-V conduction

Category: Pharmacology Notes