HIV: Class-specific toxicity
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You are here: Home » Medical Subject Notes , Pharmacology Notes » HIV: Class-specific toxicity
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Nucleosides analogues |
Inhibition of mitochondrial DNA-polymerase: Lactic acidosis (Krebs cycle in mitochondria disturbed), cardiomyopathy, peripheral neuropathy, liver steatosis, pancreatitis. |
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Nucleotides analogues |
Renal tubular toxicity: Fanconi-like syndrome (reversible) |
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Non-nucleosides RT inhibitors |
Hypersensitivity reactions (first 6 weeks) |
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Protease inhibitors |
Lipodystrophy, hypertriglyceridaemie, glucose intolerance |
Category: Medical Subject Notes , Pharmacology Notes
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