Principles of immunosuppression in transplantation

on 17.3.09 with 0 comments



  • at the time of transplantation

    • use some combination of immunosuppressive drugs with antilymphocyte treatment (monoclonal or polyclonal Ab)

  • maintenance immunosuppression

    • glucocorticoids, calcineurin inhibitor, antimetabolite

    • sirolimus used to limit exposure to nephrotoxic calcineurin inhibitors

  • treatment of rejection

    • tailored to the organ transplanted


Category: Medical Subject Notes , Pathology Notes

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