Chemical injuries resulting in hemolysis
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You are here: Home » Medical Subject Notes , Pathology Notes » Chemical injuries resulting in hemolysis
Lead poisoning
Lead interferes with aminolevulinic acid dehydratase and ferroketolase, which are involved in incorporating iron into the heme molecule
Instead, the iron is put into zinc-protoporphyrin or free erythrocyte protoporphyrin, both of which are increased
There is a microcytic, hypochromic, hemolytic anemia with coarse basophilic stippling of the erythrocytes
Other chemicals like sulfas, pyridium, furadantin, salicylates, mothballs, arsine, copper, etc
Category: Medical Subject Notes , Pathology Notes
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