ANCA
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You are here: Home » Medical Subject Notes , Pathology Notes » ANCA
antineutrophil cytoplasmic antibodies
these are circulating antibodies that react with constituents of the patient’s own neutrophils
types
cytoplasmic ANCA
granular staining in the cytoplasm
ab against serine proteinase 3, a neutrophil granule constituent
the basis for Wegener’s granulomatosis
perinuclear ANCA
neutrophil cytoplasm itself does not stain
ab against myeloperoxidase
Category: Medical Subject Notes , Pathology Notes
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