Major disorders associated with DIC

• Obstetric complications such as abruptio placentae, retained dead fetus, septic abortion, amniotic fluid embolism, and toxemia of pregnancy (placental microthrombi)

• Infections like G(-) sepsis, menigococcemia (Waterhouse-Friderichsen syndrome; acute adrenal hemorrhage/necrosis), RMSF, histoplasmosis, aspergillosis, and malaria

• Neoplasms like mucinous adenocarcinomas of the pancreas, prostate, ovary, lungs, and stomach, or acute promyelocytic leukemia

• Massive tissue injuries such as trauma, burns, and extensive surgery

• Miscellaneous conditions

  • Acute intravascular hemolysis (as in transfusion reaction)

  • Snakebite

  • Giant hemangioma

  • Shock

  • Heat stroke

  • Vasculitis

  • Aortic aneurysm

  • Liver disease

Category: Medical Subject Notes , Pathology Notes