Glomerulonephritis in Subacute Bacterial Endocarditis
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Know the etiologic agents, histology, and pathogenesis of Subacute Bacterial Endocarditis (SABE) glomerulonephritis
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Etiologic Agents – most common
- Staph aureus
- Strep viridans
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Histology
- Light Microscopy - Focal proliferative GN often w/ necrosis and intracapillary thrombi to crescentic GN
- Immuno Fluorescence - Granular deposits of IgG, IgM, and C3 in mesangial and subendothelial areas
- Pathogenesis – Immune complex, NOT infectious emboli
What is shunt nephritis?
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Syndrome similar to SABE seen in patients with ventriculoatrial shunts
Category: Pathology Notes
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