CORONAVIRIDAE: HUMAN CORONAVIRUS
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STRUCTURE: ss (+) RNA, lipid envelope, "crown-like," more than twice as large as Picornaviridae.
DIAGNOSIS: It isn't cultured, but must distinguish it from bacterial otitis media or pharyngitis. Culture for Strep-A.
IMMUNITY: Acquired immunity is poor; reinfection with same strain occurs.
MANIFESTATIONS:
Common Cold: 10-15% of cases, peaking in winter / spring months.
Category: Microbiology Notes
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