Trypanosomiasis: Comparison of detection thresholds

on 4.12.08 with 0 comments





Technique

Sensitivity

Fresh blood preparation (10 µl)

6000 trypanosomes/ml

Thick drop (10 l)

2000 trypanosomes/ml

Buffy coat (70 l)

600 trypanosomes/ml

QBC (Quantitative Buffy Coat Test)

16 trypanosomes/ml (to be confirmed, probably less sensitive)

MAECT (500 l)

6 trypanosomes/ml (extreme; in reality usually 100/ml required)

PCR (Polymerase Chain Reaction)

10 trypanosomes/ml (to be confirmed)

KIVI

1 trypanosome per 5 ml.


Category: Medicine Notes

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