Direct consequences of the increasing resistance of P. falciparum malaria:

on 6.10.08 with 0 comments




  • an increase in mortality and morbidity

  • a delayed initial therapeutic response

  • a shorter interval before recrudescence occurs.



Example:


Evolution of cure rate of falciparum malaria in Thailand

If the distribution of anti-malaria agents could be more strictly regulated in malaria regions, the rate at which resistance is spreading might be slowed down. However, the availability of these drugs via the private sector works against this proposal. As regards prophylaxis, this could either be limited to strictly selected groups and provoking the use of stand-by treatments. The use of primaquine could be promoted to counteract transmission (primaquine is a gametocytocide).

Category: Medicine Notes

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