Cardiac Arrhythmias: Proarrhythmics
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10.10.08
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all antiarrhythmics can be proarrhythmic, which means they can cause arrhythmias when they’re trying to suppress it. this is bad
most commonly assoc with class I Na-channel blockers and class III K-channel blockers, except for amiodarone, which is rarely pro-arrhythmic
induced arrhythmias can be fatal (e.g. torsades de pointes due to ventricular reentry from QT prolongation, seen in class III drugs)
Category: Pharmacology Notes
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