Therapeutic Uses : Radioactive Iodine

on 14.9.08 with 0 comments



Sodium iodide I 131is available as a solution or in capsules containing essentially carrier-free 131I suitable for oral administration. Sodium iodide I 123 is available for scanning procedures. Radioactive iodine finds its widest use in the treatment of hyperthyroidism and in the diagnosis of disorders of thyroid function. Discussion will be limited to the uses of 131I.


Hyperthyroidism. Radioactive iodine is highly useful in the treatment of hyperthyroidism, and in many circumstances it is regarded as the therapeutic procedure of choice for this condition. The use of iodide as treatment for hyperthyroidism, however, may preclude, for months, treatment and certain imaging studies with radioactive iodine.


Dosage and Technique-131I is administered orally, and the effective dose differs for individual patients. It depends primarily upon the size of the thyroid, the iodine uptake of the gland, and the rate of release of radioactive iodine from the gland subsequent to its deposition in the colloid.

Category: Pharmacology Notes

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