Lung Cancer : Squamous Cell Carcinoma
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You are here: Home » Pathology Notes » Lung Cancer : Squamous Cell Carcinoma
- This accounts for about 45% of lung cancer cases.
- It is strongly correlated to a smoking history. It usually arises in the larger bronchi, more proximally.
- It is recognised by presence of individual cell keratinisation (keratin production causes cell death) and intercellular bridges.
- This type of cancer is commonly associated with: Pancoast tumour (i.e.: apical lung tumours in the superior pulmonary sulcus that tend to invade the neural structures around the trachea, cervical sympathetic plexus), hypercalcaemia.
- SCC is least likely to metastatize, at autopsy 50% of cases are confined to the thorax.
- This type of cancer may respond well to surgery.
Category: Pathology Notes
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