General Anesthetics: METHOXYFLURANE
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-Oswald Coefficient = 13, slow induction/emergence; not used for induction/emergence but for maintenance
-can cause hypotension similar to halothane
-very fat soluble
-HIGHLY METABOLISED (60%) IN LIVER, F- released from liver metabolism; metabolised in the liver because high Oswald coefficient. Must limit dose and duration. Also toxic to kidney.
-excellent analgesic, similar in effect to ether
-excellent muscle relaxant; best among the halogenated compounds!
Category: Pharmacology Notes
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