Zaleplon & Zopiclone
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9.3.08
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Nonbenzodiazepine agonist that acts at the GABAA1 receptors to exert actions similar to benzo’s
Short half-life
Only approx. 30% of an orally administered dose reaches the plasma, and most of that undergoes first-pass elimination
Half as potent as zolpidem
Improves sleep quality w/o rebound insomnia, and little chance of developing dependency
Category: Pharmacology Notes
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